Prof. Anthony Cleare

Professor Anthony Cleare is a Professor of Psychopharmacology and Affective Disorders at King’s College London, and a consultant psychiatrist in The National Affective Disorders Service at the Maudsley Hospital.

He regularly features in the national media, providing comment on topical mental health stories, for example, a study on the use of antidepressants and on new approaches to treating depression.

Professor Cleare qualified in medicine at Guy’s Hospital, before training in psychiatry at the Maudsley, Bethlem Royal and King’s College Hospitals, winning the Laughlin Prize of the Royal College of Psychiatrists. He was appointed a consultant at the Maudsley in 1998. 

He carried out his academic training at the Institute of Psychiatry at King’s College London, where he was appointed clinical senior lecturer as well as holding a senior research fellowship, before obtaining his Chair in 2011. He also spent time at the Hammersmith Hospital and Imperial College London’s Positron Emission Tomography (PET) Unit.

Professor Cleare is a Principle Investigator in the NIHR Maudsley Biomedical Research Centre, which researches new tests, treatments and theories in mental health, neurology and dementia. He is also Co-Director of the Centre for Affective Disorders, which focuses on mood and anxiety disorders and tries to understand the science related to these illnesses, and use the knowledge to help develop new treatments, both psychological and pharmacological.

Having previously run the inpatient Affective Disorders Unit at the Bethlem Royal Hospital, he now leads a tertiary referral outpatient service for affective disorders. He is also Consultant Advisor in Aviation Psychiatry to the Civil Aviation Authority.

The main focus of Professor Cleare’s research is to continue work that improves the understanding of aetiology, neurobiology and long-term outcome of treatment-resistant depression. Professor Cleare’s research group is also interested in developing biomarkers for depression.

He is the research group leader for the Affective Disorders Research Group, which works to understand more about the neurobiological causes of mood disorders and mental illnesses where the normal functioning of mood is disrupted, such as clinical depression and bipolar disorder.

Other research interests include clinical psychopharmacology, chronic fatigue syndrome, aggression and neuroimaging of serotonin receptor function.

Professor Cleare has over 380 peer reviewed and other publications, and has often contributed to books and national guidelines, including the British Association for Psychopharmacology Evidence-Based Guidelines for treating depressive disorders.